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The Museum was created to collect, preserve and exhibit archaeological finds from in and around Ascoli Piceno, the Tesino Valley, the Tronto Valley and the northern part of the Province of Teramo, which was under Ascoli’s influence in the XIX century. The Museum is housed in the XVI-century Palazzo Panichi, in Piazza Arringo. The main room of the Museum features the original frescoes once on the building’s façade.