NEMO Science Museum is a science center in Amsterdam, Netherlands. It is located at the Oosterdok in Amsterdam-Centrum, situated between the Oosterdokseiland and Kattenburg. The museum has its origins in 1923, and is housed in a building designed by Renzo Piano since 1997. It contains five floors of hands-on science exhibitions and is the largest science center in the Netherlands. It attracts annually over 500,000 visitors, which makes it the fifth most visited museum in the Netherlands.